Flexible electronic skin, as an important part of bionic technology, has a wide range of applications in the fields of wearable devices, intelligent robots, and bionic prostheses. Graphene, as a two-dimensional material with excellent electrical conductivity, mechanical flexibility and chemical stability, shows great potential in flexible electronic skin. This paper reviews recent advances in flexible electronic skin based on graphene and its composites, presenting the unique physicochemical properties of graphene and its advantages in flexible sensor materials. This paper discusses in detail the application of graphene and its composites in flexible sensors, including pressure sensors, humidity sensors, and flexible supercapacitors. This paper summarizes the challenges faced in current research, such as the cost and process complexity of material preparation, increased sensor integration, and issues of long-term stability. In addition, this paper proposes future directions, including the large-scale preparation of low-cost and high-performance graphene materials, the improvement of sensor sensitivity and durability, the optimization of graphene composites, and the realization of multifunctional and integrated flexible e-skin systems. Valuable references are provided to further promote the practical applications of graphene-based flexible electronic skin in the fields of medical monitoring, bionic technology and smart wearable.