Investigate the role of oridonin in esophageal cancer and candida albicans

Abstract

This paper focus on the esophageal cancer, in China, 150000 people died from the esophageal cancer every year, it also has high mortality rate in the world. This report will investigate whether traditional Chinese medicine oridonin (ORI) has an impact on esophageal cancer. Assuming that VX2 (cell line) tumor size and Candida Albicans (CA) are reduced by ORI, ORI will decrease the levels of TNF-α and IL1. We will conduct experiments on rabbits to determine the quantity of CA and TNF-α and IL1 production cytokines through EILSA and endoscopic experiments, and investigate whether these cytokines can cause CA or VX2 cancer. This study will contribute to the development and connection of ORI treat esophageal cancer.