Reg family proteins, C-type lectin domains, clinical application challenges
Abstract
The Reg family all contain C-type lectin domains, which have various functions, including anti-inflammatory, antibacterial, anti-apoptotic and immunomodulatory functions. It plays a role in the liver, intestines, pancreas, lungs and nervous system. Researchers have identified 18 Reg genes and have a potential positive effect on diabetes, infections, diseases, cancer and other diseases, but cannot be used in clinical treatment. This paper first introduce the discovery process and main characteristics of reg gene proteins, and then discuss their function and current role in disease. This article provides a brief summary for those who want to understand the reg gene protein. This article has compiled the characteristics, functions, and current effects on disease of the reg gene family for the convenience of those who wish to understand them However, as a drug, reg gene protein is not mature enough, and its specificity of expression in different organs still needs to be further studied, as well as its administration dose, administration time and side effects as a drug, a large number of experiments are needed to study, which will be the direction of future research.
