Inhibiting the Expression of Cyclin D1 Protein to Reduce the HBVDNA Level in CHB patients

Abstract

HBV virus is now affecting over 400 million people worldwide. Chronic Hepatitis B (CHB) is one of the significant clinical symptoms of HBV infection. Previous studies have reported that antiviral therapy is a practical method for patients. However, the current treatment has reached a bottleneck due to economic burden and drug resistance. As a practical component in ligustrum lucidum, ursolic acid has been found to have an antiviral effect. This study focuses on one particular mechanism of its effect. It tests its function in reducing the expression of Cyclin D1 protein to provide a possible reason for its ability to inhibit cell proliferation.