New Approaches for the Synthesis of Cleistanthol

Authors

  • Yichun Wu Author
  • Xiaoyu Huang Author

DOI:

https://doi.org/10.61173/ycjej627

Keywords:

Cleistanthol, sauropus spatulifolius, diterpenoids, synthesis, retrosynthesis

Abstract

An article published on 15 April 2022 isolated cleistanthol from Sauropus spatulifolius. This report will present one of the first few new approaches for synthesizing cleistanthol and how the approach is derived by retrosynthetic analysis, along with discussions on the weaknesses of this approach and suggestions for possible improvements. Sauropus spatulifolius, often used in traditional Chinese medicine, is expected to play a role in treating some diseases of the respiratory system. To make the medicine more efficient and targeted, this work is committed to excogitate a convenient approach to synthesize an abstract of sauropus spatulifolius, cleistanthol, in high yield. The approach takes stereostructure into account so as to be utilized in pharmacy. 

Downloads

Published

2023-06-01

Issue

Section

Articles